It's over for Avandia

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Think that the Internet has not played a role in the decline in sales of Avandia? Think again. I had the chance to talk to three physicians last week about Avandia and they have switched all their diabetes patients from Avandia to other medications. As one physician told me "why take a chance with my patients health?".



For medical care I go to an Urgent Care Center here in California. The team of three physicians that meets with patients is great. You never need an appointment and it's easy to get my rx's filled. When business is slow we talk "shop" since they know I work in healthcare. When I brought up the subject of Avandia my physician told me that they had taken all their patients off the medication. "It's all over the Internet" she said, "and I have talked to colleagues on eMail. I just don't want to take the risk with my patients". I asked her if GSK has been in to see their practice to respond and she said "we haven't heard anything from them".



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So this week the FDA is looking for outside guidance on whether Avandia should continue to be approved and if so what warnings it should have on the label. However even in the best scenario it maybe too late for GSK to resurrect the Avandia business. Perception is reality and the perception is that Avandia is more risky than other drugs. In addition the generics are less pricey and patients may ask "why take the risk?".


GSK has been on the defensive ever since the first news story about Avandia was posted on the Web. What puzzles me is why didn't they see this coming and have a scenario plan in place? Was it better to pretend this data didn't exist and bury it in a mound of data? Once again pharma ignores transparency and thinks that they can keep information hidden from physicians and the public. It's better to be naked in with your data than try and hide things in hope that it will never be found.


So Avandia sales are continuing to plummet and no doubt that GSK will soon announce some job cuts to keep the street happy. Maybe they will learn from this experience or maybe they will continue to be in a state of denial about the realities of empowered consumers and physicians.

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